About me

• Investigator (Biostatistics) @ TIMI Study Group / Brigham and Womens Hospital
• Lecturer at Harvard Medical School / Harvard T.H. Chan School of Public Health

Research

My research focuses on the application of statistical and machine learning approaches for the assessment of complex predictors and interactions in precision cardiovascular medicine and exposome-wide analysis. More details and several slides of recent talks and presentations are available here

Software

• R, SAS, and Stata functions to incorporate non-linear and non-additive effects in regression models with restricted cubic splines
• interactionRCS: R functions to smoothly plot the effect of a predictor of interest over levels of a second continuous covariate after specifying flexible interactions in regression models
• med4way: a Stata command for estimating the 4-way decomposition of the total effect in mediation analysis

Publications

Recent Publications

• Discacciati A, Palazzolo MG, Park JG, Melloni, GEM, Murphy SA, Bellavia A. Estimating and Presenting Non-Linear Associations with Restricted Cubic Splines. International Journal of Epidemiology

• Bellavia A, Murphy SA. Clinical Interpretation of Statistical Interaction. Circulation

• Bellavia A, Murphy SA. Cox Regression Model in Clinical Research: Overview of Key Properties and Interpretation. Circulation

• Bellavia A, Ran X, Zimerman A, Antman EM, Giugliano RP, Morow DA, Murphy SA. Unsupervised clustering approach to assess heterogeneity of treatment effects across patient phenotypes in randomized clinical trials. Contemporary Clinical Trials

• Haller P, Jarolim P, Palazzolo MG, Bellavia A, Antman E, Eikelboom J, Granger C, Harrington J, Healey J, Hijazi Z, Patel M, Patel S, Ruff C, Wallentin L, Braunwald E, Giugliano RP, Morrow DA. Heart failure risk assessment using biomarkers in patients with atrial fibrillation: Analysis from COMBINE-AF. Journal of the American College of Cardiology

Full list of publications: link

Textbook

Statistical Methods for Environmental Mixtures: A Primer in Environmental Epidemiology. Springer, 2024

Accompanying R material available here

Teaching

• Harvard T.H. Chan School of Public Health - EPI236: Analytic Issues of Clinical Epidemiology, Summer Program in Clinical Effectiveness (2024-)
• Harvard T.H. Chan School of Public Health - EH245: Statistical Methods for Environmental Mixtures and Exposome Research (2019-)
• Summer School on Modern Methods in Biostatistics and Epidemiology - Mediation Analysis (2018-)